Nixus, Lord of Venom

+1: Put a -1/-1 counter on target creature, then that creatures controller loses 1 life for each -1/-1 counter on target creature.
-X: Remove or place X -1/-1 counters, +1/+1 counters or Loyalty counters on target creature or planeswalker.
-8: Put a -1/-1 counter on each creature your opponents control, then you may destroy any number of creatures with -1/-1 counters on them.