Penicilin G

Destroy target : Gram positive aerobes (S.Pyogenes, S.Pneumoniae) Gram negative cocci (N.Meningitidis),Spirochetes (T.Pallidum), Branching gram-positive anaerobes (Actinomyces) Creatures
Inhibits Penicillin Binding proteins, resulting in lower crosslinking in peptidoglycan layer of cell walls.
Resistance via B-lactamase, or PBP Mutation
"All this from a piece of toast"
—Amox"icillin"