Ylthreii Ve'l, Void Primogenit

Nihility - When this spell is cast, if the mana cost
of this spell was paid using only mana from
sources that can produce only colorless mana,
each player loses life equal to the number of
colored mana symbols in the mana costs of permanents they control.
At the beginning of each player's upkeep, that
player loses life equal to the number of colors
among permanents they control.